LncRNA MIR155HG suppresses cell apoptosis by activating autophagy via miR-7036b-3p/GPNMB axis and AMPK/mTOR signaling in spinal cord injury

LncRNA MIR155HG suppresses cell apoptosis by activating autophagy via miR-7036b-3p/GPNMB axis and AMPK/mTOR signaling in spinal cord injury

Background: Long non-coding RNAs (lncRNAs) participate in spinal cord injury (SCI) development through regulating autophagy and neuronal apoptosis. Previously, MIR155HG was identified as an upregulated lncRNA in rat bladder tissues harvested after SCI operation. Our study aimed to elucidate the func...

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Bibliographic Details
Main Authors: Ruoxi Liu, Jintao Ye, Sihua Huang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-12-01
Series:Non-coding RNA Research
Subjects:
Spinal cord injury
MIR155HG
GPNMB
AMPK/mTOR
Apoptosis
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054025000678
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