Altered expression and potential role of N6-methyladenosine mRNA methylation in abdominal aortic aneurysm mouse model

Altered expression and potential role of N6-methyladenosine mRNA methylation in abdominal aortic aneurysm mouse model

Abstract It is an important cause of death in old age to rupture an abdominal aortic aneurysm. The pathogenesis of AAA has not been fully elucidated, and m6A RNA methylation regulators have never been implicated in AAA development. This study aimed to explore the expression profile, potential functi...

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Bibliographic Details
Main Authors: Julin Wang, Tianyu Miao, Yanyun Wang, Tiehao Wang, Zhangyu He, Fei Xiong, Ding Yuan, Qiang Guo, Yi Yang, Zhichen Tang, Bin Huang, Jichun Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Abdominal aortic aneurysm
m6A
Methylation
Mice model
Wnt pathway
mRNA
Online Access:https://doi.org/10.1038/s41598-025-03760-8
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https://doi.org/10.1038/s41598-025-03760-8

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