Mismatch uracil DNA glycosylase (Mug) is maintained in the Corynebacterium pseudotuberculosis genome and exhibits affinity for uracil but not other types of damage

Mismatch uracil DNA glycosylase (Mug) is maintained in the Corynebacterium pseudotuberculosis genome and exhibits affinity for uracil but not other types of damage

Abstract The genome of Corynebacterium pseudotuberculosis, etiologic agent of Caseous Lymphadenitis (CLA), was sequenced to comprehend its genetics, pathogenicity, and virulence mechanisms due to its economic importance. A focus was placed on the G/U mismatch-specific DNA glycosylase (Mug), an enzym...

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Bibliographic Details
Main Authors: Bruno Carvalho Resende, Cássio Siqueira Souza Cassiano, Diego Lisboa Rios, Thalia Queiroz Ladeira, Vasco Ariston Carvalho Azevedo, Luciana Lara dos Santos, Lucía Valenzuela-Pérez, Gonzalo Cabrera, Carlos Renato Machado, Débora de Oliveira Lopes
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2025-04-01
Series:Genetics and Molecular Biology
Subjects:
Uracil
G/U mismatch-specific DNA glycosylase
Corynebaterium pseudotuberculosis
DNA repair
base excision repair
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572025000200401&lng=en&tlng=en
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