Mechanistic insights into the role of FAT10 in modulating NCOA4-mediated ferroptosis in pancreatic acinar cells during acute pancreatitis

Abstract Acute pancreatitis (AP) is characterised by inflammation and cell death in pancreatic tissue, with ferroptosis playing a critical role in its pathophysiology by mediating cellular damage and exacerbating inflammation. This study investigated the role of human leukocyte antigen (HLA)-F adjac...

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Main Authors: Lingpeng Liu, Ben Che, Wenming Zhang, Dongnian Du, Dandan Zhang, Jiajuan Li, Zehao Chen, Xuzhe Yu, Miao Ye, Wei Wang, Zijing Li, Fei Xie, Qing Wang, Leifeng Chen, Jianghua Shao
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07715-9
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