METTL14 and FTO mediated m6A modification regulate PCV2 replication by affecting miR-30a-5p maturity

METTL14 and FTO mediated m6A modification regulate PCV2 replication by affecting miR-30a-5p maturity

The epigenetic modification of the N6-methyladenosine (m6A) methylation plays an important role in virus infection and replication. However, its role in Porcine circovirus type 2 (PCV2) replication has not been well studied. Here, we demonstrated that m6A modifications are increased in PK-15 cells a...

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Bibliographic Details
Main Authors: Chen Li, Xiaoyan Wu, Ying Yang, Jianli Shi, Shuo Wang, Jiaxin Li, Yao Tian, Chang Liu, Hong Han, Shaojian Xu, Xianjie Han, Yingru Ma, Limei Zheng, Jun Li
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
Porcine circovirus type 2
m6A modification
miRNA maturity
replication
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2232910
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https://www.tandfonline.com/doi/10.1080/21505594.2023.2232910

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