Effects and mechanisms of liraglutide in ameliorating liver fibrosis in NAFLD mice

Effects and mechanisms of liraglutide in ameliorating liver fibrosis in NAFLD mice

Objective·To investigate the effects of liraglutide on liver fibrosis in mice with non-alcoholic fatty liver disease (NAFLD) and the underlying mechanisms.Methods·Twenty 8-week-old C57BL/6J mice were randomly divided into a normal chow diet group (Chow group) and a methionine-choline-deficient (MCD)...

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Bibliographic Details
Main Authors: WANG Renjie, ZHU Chaoyu, FANG Yunyun, XIAO Yuanyuan, WANG Qianqian, SONG Wenjing, WEI Li
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2025-04-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:
liraglutide
transforming growth factor-β (tgf-β)
sma- and mad-related protein 3 (smad3)
non-alcoholic fatty liver disease
liver fibrosis
Online Access:https://xuebao.shsmu.edu.cn/article/2025/1674-8115/1674-8115-2025-45-4-415.shtml
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