Sex differences in the association between Life’s Essential 8 and serum anti-aging Klotho protein levels: a cross-sectional analysis in middle-aged to older adults

Sex differences in the association between Life’s Essential 8 and serum anti-aging Klotho protein levels: a cross-sectional analysis in middle-aged to older adults

BackgroundThis study explores the association between cardiovascular health metrics (Life’s Essential 8, LE8) and serum anti-aging Klotho protein levels among American adults aged 40–79, with a focus on sex-specific differences.MethodsUtilizing data from the 2007–2016 National Health and Nutrition E...

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Bibliographic Details
Main Authors: Jing Zeng, Tingting Zhang, Yan Yang, Jinjing Wang, Xiaojing Fan, Qiaomin Wang, Xuan Wang, Haoxian Tang, Yi Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Aging
Subjects:
sex differences
Life's Essential 8
cardiovascular health
Klotho
aging
NHANES
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2025.1458571/full
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https://www.frontiersin.org/articles/10.3389/fragi.2025.1458571/full

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