High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations.

High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, given the well-known and widespread phenomenon of g...

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Bibliographic Details
Main Authors: Celia Payen, Anna B Sunshine, Giang T Ong, Jamie L Pogachar, Wei Zhao, Maitreya J Dunham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006339&type=printable
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