157Gd-DOTA-PSMA as theranostic bio-gadolinium agent for prostate cancer targeted gadolinium neutron capture therapy

157Gd-DOTA-PSMA as theranostic bio-gadolinium agent for prostate cancer targeted gadolinium neutron capture therapy

Abstract Purpose Gadolinium-neutron capture therapy (Gd-NCT) employs isotopically enriched Gadolinium (Gd) and thermal neutrons to selectively target cancer cells. This study investigated the targeting efficacy of 157Gd-DOTA-PSMA (Prostate-Specific Membrane Antigen) in prostate cancer and explored i...

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Main Authors: Liang Xie, Jialin Qin, Cuiping Song, Jianchun Yin, Ruixue Wu, Hong Chen, Yujie Dong, Nianfei Wang, Lei Chen, Bing Hong, Ni Chen, Peng Lu, Fei Li, Xiaoxi Pang
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Neutron capture therapy
PSMA
Prostate cancer
PET/CT
MRI
Molecular imaging
Online Access:https://doi.org/10.1007/s00432-025-06136-7
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https://doi.org/10.1007/s00432-025-06136-7

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