Dynamics of stochastic mutation to immunodominance
Although a virus contains several epitopes that can be recognized by cytotoxic T lymphocytes (CTL), the immune responses against different epitopes are not uniform. Only a few CTLs (sometimes just one) will be immunodominant. Mutation of epitopes has been recognized as an important mechanism of immu...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2012-09-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.937 |
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