Dynamics of stochastic mutation to immunodominance

Although a virus contains several epitopes that can be recognized by cytotoxic T lymphocytes (CTL), the immune responses against different epitopes are not uniform. Only a few CTLs (sometimes just one) will be immunodominant. Mutation of epitopes has been recognized as an important mechanism of immu...

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Bibliographic Details
Main Authors: Yu Wu, Xiaopeng Zhao, Mingjun Zhang
Format: Article
Language:English
Published: AIMS Press 2012-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.937
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