Modeling CSF circulation and the glymphatic system during infusion using subject specific intracranial pressures and brain geometries

Modeling CSF circulation and the glymphatic system during infusion using subject specific intracranial pressures and brain geometries

Abstract Background Infusion testing is an established method for assessing CSF resistance in patients with idiopathic normal pressure hydrocephalus (iNPH). To what extent the increased resistance is related to the glymphatic system is an open question. Here we introduce a computational model that i...

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Bibliographic Details
Main Authors: Lars Willas Dreyer, Anders Eklund, Marie E. Rognes, Jan Malm, Sara Qvarlander, Karen-Helene Støverud, Kent-Andre Mardal, Vegard Vinje
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Fluids and Barriers of the CNS
Subjects:
Infusion test
CSF circulation
Glymphatic pathway
CSF dynamics
Intracranial pressure
Paravascular flow
Online Access:https://doi.org/10.1186/s12987-024-00582-0
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https://doi.org/10.1186/s12987-024-00582-0

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