Parkinson’s Disease: A Narrative of the Evolving Understanding of the Role of α-Synuclein in Screening

Parkinson’s Disease: A Narrative of the Evolving Understanding of the Role of α-Synuclein in Screening

The present investigation aims to examine the role of α-synuclein seed amplification assays for screening Parkinson’s disease. Parkinson’s disease (PD) is a debilitating neurodegenerative disorder caused by the loss of dopaminergic neurons in the midbrain, leading to symptoms such as tremors, bradyk...

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Bibliographic Details
Main Authors: Alan D. Kaye, Kassady A. Perkinson, Noah J. Spillers, Alexis J. Vega, Caylin J. Roberts, Evan M. Downs, Melissa M. Sheth, David W. McGregor, Shahab Ahmadzadeh, Jibin Mathew, Sahar Shekoohi
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Current Issues in Molecular Biology
Subjects:
α-synuclein
Parkinson’s disease screening
seeding
amplification assay
Online Access:https://www.mdpi.com/1467-3045/46/11/757
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