Adipose tissue-associated Krt23+fibroblasts contribute to immune microenvironment disorders in mouse adipose tissue during the development of obesity

Abstract Obesity alters the adipose tissue (AT) immune microenvironment (TIME) and induces inflammation. Nevertheless, the specific time when TIME dysfunction emerges in AT remains elusive. Obesity mouse models were constructed and categorized into Lean (Ctrl), moderately obese (Mid_Ob, with body we...

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Bibliographic Details
Main Authors: Zhimin Lu, Ling Ding, Sen Zhang, Xing Jiang, Wen Ma, Youhan Liu, Xuewen Tian, Qinglu Wang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02978-6
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