Batf3-cDC1 control Th1 and fungicidal responses during cryptococcal meningitis: is this enough to control meningitis?

ABSTRACT Dendritic cells are crucial for bridging innate and adaptive immunity. Cryptococcosis, caused by Cryptococcus neoformans and Cryptococcus gattii, is responsible for >15% of AIDS-related deaths. A recent study by Xu et al. showed that Batf3-dependent conventional type 1 dendritic (cDC1) c...

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Bibliographic Details
Main Author: Carolina Coelho
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00375-24
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