Isolation and Identification of <i>Cis-</i>2,5-Diketopiperazine from a Novel <i>Bacillus</i> Strain and Synthesis of Its Four Stereoisomers

Isolation and Identification of <i>Cis-</i>2,5-Diketopiperazine from a Novel <i>Bacillus</i> Strain and Synthesis of Its Four Stereoisomers

The <i>Bacillus horneckiae</i>-like strain 2011SOCCUF3 was isolated from the marine sponge <i>Spongia officinalis</i> and its metabolome was studied for secondary metabolites with antimicrobial activity. Culturing in the presence of Diaion HP-20 resin and purifying the cultur...

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Main Authors: Alan M. C. Obled, Refaat B. Hamed, Edward Spence, Marija K. Zacharova, Sunil V. Sharma, Yunpeng Wang, Rosemary Lynch, Helen Connaris, Adina Tatheer, Marie-Lise Bourguet-Kondracki, Gordon J. Florence, Rebecca J. M. Goss
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Marine Drugs
Subjects:
<i>Bacillus</i>
marine sponge bacteria
diketopiperazine
cyclopeptide
antimicrobial
Online Access:https://www.mdpi.com/1660-3397/23/6/234
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