Mechanisms Mediating the Effects of γ-Tocotrienol When Used in Combination with PPARγ Agonists or Antagonists on MCF-7 and MDA-MB-231 Breast Cancer Cells

γ-Tocotrienol is a natural vitamin E that displays potent anticancer activity, and previous studies suggest that these effects involve alterations in PPARγ activity. Treatment with 0.5–6 μM  γ-tocotrienol, 0.4–50 μM PPARγ agonists (rosiglitazone or troglitazone), or 0.4–25 μM PPARγ antagonists (GW96...

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Bibliographic Details
Main Authors: Abhita Malaviya, Paul W. Sylvester
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2013/101705
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