An immediate–late gene expression module decodes ERK signal duration

An immediate–late gene expression module decodes ERK signal duration

Abstract The RAF‐MEK‐ERK signalling pathway controls fundamental, often opposing cellular processes such as proliferation and apoptosis. Signal duration has been identified to play a decisive role in these cell fate decisions. However, it remains unclear how the different early and late responding g...

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Bibliographic Details
Main Authors: Florian Uhlitz, Anja Sieber, Emanuel Wyler, Raphaela Fritsche‐Guenther, Johannes Meisig, Markus Landthaler, Bertram Klinger, Nils Blüthgen
Format: Article
Language:English
Published: Springer Nature 2017-05-01
Series:Molecular Systems Biology
Subjects:
ERK signalling
immediate–late genes
mRNA half‐life
signal decoding
signal duration
Online Access:https://doi.org/10.15252/msb.20177554
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https://doi.org/10.15252/msb.20177554

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