Targeted Suppression of CEACAM6 via pHLIP-Delivered RNAs in Pancreatic Ductal Adenocarcinoma

Targeted Suppression of CEACAM6 via pHLIP-Delivered RNAs in Pancreatic Ductal Adenocarcinoma

<i>Background and Objectives</i>: Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is involved in pancreatic cancer progression and is an attractive therapeutic target for pancreatic cancer. In this study, we evaluated the therapeutic efficacy of small-interfering RNA...

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Main Authors: Hongsik Kim, Chang-Gok Woo, Seung-Myoung Son, Yong-Pyo Lee, Hee-Kyung Kim, Yaewon Yang, Jihyun Kwon, Ki-Hyeong Lee, Ho-Chang Lee, Ok-Jun Lee, Hye-Sook Han
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Medicina
Subjects:
pancreatic ductal adenocarcinoma
pHLIP
CEACAM6
drug delivery
tumor acidity
Online Access:https://www.mdpi.com/1648-9144/61/4/598
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