The lower rate of bone and joint infection in patients with open extremity fractures associated with vaccination prior to injury: a propensity-matched cohort study

BackgroundVaccines could strengthen the innate immune system in addition to conferring protection against their target pathogen via vaccine-induced immunomodulation, a phenomenon termed trained immunity. The purpose of the present study was to determine whether vaccination prior to injury is associa...

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Bibliographic Details
Main Authors: Wencheng Hu, Saiyu Shi, Junqing Lin, Tao Gao, Junjie Shen, Yi Sun, Haifeng Wei, Xianyou Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1546191/full
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