Synthesis and Application of a New Cyclic Phosphoric Acid in Enantioselective Three-Component Mannich Reactions

A novel point-chiral six-membered cyclic phosphoric acid was synthesized starting from an enantiopure precursor via a concise three-step route. Its catalytic performance was evaluated in enantioselective three-component Mannich reactions. Under optimized conditions, the catalyst provided good yields...

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Bibliographic Details
Main Authors: Giovanni Ghigo, Alessio Robiolio Bose, Stefano Dughera
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/14/2928
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