miR-374-5p inhibits osteogenesis by targeting PTEN/PI3K/AKT signaling pathway
Abstract Purpose This study aims to evaluate the effects of miR-374-5p on osteogenesis in rat osteoblasts, validate its target on PTEN, and explore its role in the PTEN/PI3K/AKT signaling pathway during osteoblast differentiation. Methods We transfected 293T cells with miR-374-5p mimics and inhibito...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-025-05670-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|