Early neural dysfunction reflected in degraded auditory cortex responses in pre-regression heterozygous Mecp2 rats

Rett syndrome, a genetic disorder caused by mutations in the X-linked Mecp2 gene, is characterized by typical early development followed by rapid developmental regression between 6 and 18 months of age. Affected individuals exhibit seizures, cognitive impairments, motor deficits, and difficulties in...

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Bibliographic Details
Main Authors: Yuko Tamaoki, Samantha L. Kroon, Brendan M. Williams, Jonathan R. Riley, Crystal T. Engineer
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125001421
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