The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis

ABSTRACT Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite, Toxoplasma gondii, is a widespread intracellular parasite of warm-blooded animals whose plasma membrane is covered with GPI-anchored proteins, and free GPIs cal...

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Main Authors: Julia A. Alvarez, Elisabet Gas-Pascual, Sahil Malhi, Juan C. Sánchez-Arcila, Ferdinand Ngale Njume, Hanke van der Wel, Yanlin Zhao, Laura García-López, Gabriella Ceron, Jasmine Posada, Scott P. Souza, George S. Yap, Christopher M. West, Kirk D. C. Jensen
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.00527-24
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