The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis

The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis

ABSTRACT Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite, Toxoplasma gondii, is a widespread intracellular parasite of warm-blooded animals whose plasma membrane is covered with GPI-anchored proteins, and free GPIs cal...

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Main Authors: Julia A. Alvarez, Elisabet Gas-Pascual, Sahil Malhi, Juan C. Sánchez-Arcila, Ferdinand Ngale Njume, Hanke van der Wel, Yanlin Zhao, Laura García-López, Gabriella Ceron, Jasmine Posada, Scott P. Souza, George S. Yap, Christopher M. West, Kirk D. C. Jensen
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
Subjects:
GPI
GIPL
GPI sidechain
mass spectrometry
PIGJ
PIGE
Online Access:https://journals.asm.org/doi/10.1128/mbio.00527-24
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https://journals.asm.org/doi/10.1128/mbio.00527-24

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