Frequency and Impact of Constitutional Mismatch Repair Deficiency in Patients With High-Grade Glioma, a Retrospective Analysis of 7 Years in Pakistan: an IRRDC Study

PURPOSEConstitutional mismatch repair deficiency (CMMRD) is a genetic cancer predisposition syndrome among children and young adults. This study aimed to evaluate the frequency of CMMRD among patients with pediatric high-grade glioma (pHGG) in a single tertiary care center in Pakistan, a country wit...

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Main Authors: Naureen Mushtaq, Khurram Minhas, Farrah Bashir, Soha Zahid, Bilal Mazhar Qureshi, Gohar Javed, Shahzadi Resham, Anirban Das, Cynthia Hawkins, Uri Tabori, Eric Bouffet
Format: Article
Language:English
Published: American Society of Clinical Oncology 2025-04-01
Series:JCO Global Oncology
Online Access:https://ascopubs.org/doi/10.1200/GO-24-00247
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