Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques
IntroductionMale pattern hair loss (MPHL), also known as androgenetic alopecia (AGA), is a common disorder primarily caused by dihydrotestosterone (DHT). The Food and Drug Administration (FDA) has approved two 5-alpha reductase (5-AR) inhibitors—finasteride and dutasteride—for treating this conditio...
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| Main Authors: | Behnam Hasannejad-Asl, Farkhondeh Pooresmaeil, Sareh azadi, Ali Najafi, Ali Esmaeili, Saeid Bagheri-Mohammadi, Bahram Kazemi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Bioinformatics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2025.1570101/full |
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