Hsp70: A Multifunctional Chaperone in Maintaining Proteostasis and Its Implications in Human Disease

Hsp70: A Multifunctional Chaperone in Maintaining Proteostasis and Its Implications in Human Disease

Hsp70, a 70 kDa molecular chaperone, plays a crucial role in maintaining protein homeostasis. It interacts with the DnaJ family of co-chaperones to modulate the functions of client proteins involved in various cellular processes, including transmembrane transport, extracellular vesicle trafficking,...

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Bibliographic Details
Main Authors: Manish Kumar Singh, Sunhee Han, Songhyun Ju, Jyotsna S. Ranbhise, Joohun Ha, Seung Geun Yeo, Sung Soo Kim, Insug Kang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
cancer
epichaperome
Hsp70
inflammation
apoptosis
protein-folding
Online Access:https://www.mdpi.com/2073-4409/14/7/509
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