Hypoxia‐Induced Acidification Causes Mitoxantrone Resistance Not Mediated by Drug Transporters in Human Breast Cancer Cells

Hypoxia has clinically been associated with resistance to chemotherapy. The aim of this study was to investigate whether hypoxia induces resistance to doxorubicin and mitoxantrone, two common drugs in cancer treatment, in MCF‐7 breast cancer cells, and SW1573 non‐small lung cancer cells. In addition...

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Bibliographic Details
Main Authors: A. E. Greijer, M. C. de Jong, G. L. Scheffer, A. Shvarts, P. J. van Diest, E. van der Wall
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2005/236045
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