Whole exome-seq and RNA-seq data reveal unique neoantigen profiles in Kenyan breast cancer patients

Whole exome-seq and RNA-seq data reveal unique neoantigen profiles in Kenyan breast cancer patients

BackgroundThe immune response against tumors relies on distinguishing between self and non-self, the basis of cancer immunotherapy. Neoantigens from somatic mutations are central to many immunotherapeutic strategies and understanding their landscape in breast cancer is crucial for targeted intervent...

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Bibliographic Details
Main Authors: Godfrey Wagutu, John Gitau, Kennedy Mwangi, Mary Murithi, Elias Melly, Alexandra R. Harris, Shahin Sayed, Stefan Ambs, Francis Makokha
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Oncology
Subjects:
neoantigen
breast cancer
exome-seq
RNA-seq
somatic mutations
Kenya
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1444327/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1444327/full

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