Panaxatriol saponins exert anti-renal fibrosis by suppressing TNF-α mediated inflammation and TGF-β1/Smad3 signaling pathway
Renal fibrosis is a key pathological process in the progression of chronic kidney disease (CKD). Panaxatriol saponins (PTS), the main bioactive compounds extracted from Panax notoginseng (Burk.) F.H. Chen, have demonstrated antioxidative and anti-inflammatory activities. This study aimed to investig...
Saved in:
| Main Authors: | Si Yi, Feiyan Li, Xin Ma, Yao Xu, Weijing Lai, Hongxi Chen, Junming Fan, Nan Mao, Sichong Ren |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Renal Failure |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2025.2516774 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Paridis Rhizoma Saponins ameliorate CCl4-induced liver fibrosis via modulation of the Nrf2-HO-1/NQO-1 and TGF-β1/Smads signaling pathways
by: Yan Hong, et al.
Published: (2025-06-01) -
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
by: Qian Huang, et al.
Published: (2022-09-01) -
Corrigendum: Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
by: Qian Huang, et al.
Published: (2024-12-01) -
SQLE promotes osteosarcoma progression via activating TGFβ/SMAD signaling pathway
by: Qi Song, et al.
Published: (2024-12-01) -
The promotive role of reticulocalbin 3 (RCN3) in the pathogenesis of keloid via TGFβ1/Smad2/Smad7 signaling pathway in vitro
by: Wang HongYu, et al.
Published: (2024-12-01)