Synthesis, comprehensive in silico studies, and cytotoxicity evaluation of novel quinazolinone derivatives as potential anticancer agents

Abstract Quinazolinone derivatives exhibit significant synthetic and biological properties, making them valuable candidates for anticancer drug development. In this study, we synthesized novel quinazolinone derivatives via reactions of the previously unreported 4H-benzoxazin-4-one derivative (2) wit...

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Bibliographic Details
Main Authors: David S. A. Haneen, Abdelaal A. Abdalha, Musaab M. Alkhatib, Mahmoud Kamal, Ahmed S. A. Youssef, Wael S. I. Abou-Elmagd, Sandy S. Samir
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-08062-7
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