Identification of an extracellular matrix signature for predicting prognosis and sensitivity to therapy of patients with gastric cancer

Identification of an extracellular matrix signature for predicting prognosis and sensitivity to therapy of patients with gastric cancer

Abstract Extracellular matrix (ECM) is a vital component of the tumor microenvironment and plays a crucial role in the development and progression of gastric cancer (GC). Co-expression networks were established by means of the “WGCNA” package, the optimal model for extracellular matrix scores (ECMs)...

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Bibliographic Details
Main Authors: Nan Xu, Taojing Zhang, Weiwei Sun, Chenxiao Ye, Huamiao Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Gastric cancer
Extracellular matrix
Weighted gene co-expression network analysis
Prognosis
Immunotherapy
Online Access:https://doi.org/10.1038/s41598-025-88376-8
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https://doi.org/10.1038/s41598-025-88376-8

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