Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer

Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer

Abstract Background Genome instability is a fundamental feature and hallmark of cancer, associated with aggressiveness, drug resistance and poor prognosis. RAI2 was initially identified as a novel metastasis suppressor protein specifically associated with the presence of disseminated tumour cells in...

Full description

Saved in:
Bibliographic Details
Main Authors: Lena Boettcher, Sarah Greimeier, Kerstin Borgmann, Shabbir S. Mughal, Bernhard Ellinger, Kai Bartkowiak, Bernd Zobiak, Antonio V. Failla, Pascal Steffen, Ellen Claus, Katharina Besler, Christopher Buccitelli, Violetta Schaaf, Ann-Kathrin Ozga, Simona Parretta, Svenja Schneegans, Wael Y. Mansour, Jan O. Korbel, Hartmut Schlueter, Benedikt Brors, Klaus Pantel, Harriet Wikman, Stefan Werner
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Genomic instability
Premature mitotic entry
DNA damage response
poly-(ADP-ribose)
Online Access:https://doi.org/10.1186/s13058-025-02085-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13058-025-02085-8

Similar Items