3D‐Printed Myocardium‐Specific Structure Enhances Maturation and Therapeutic Efficacy of Engineered Heart Tissue in Myocardial Infarction

3D‐Printed Myocardium‐Specific Structure Enhances Maturation and Therapeutic Efficacy of Engineered Heart Tissue in Myocardial Infarction

Abstract Despite advancements in engineered heart tissue (EHT), challenges persist in achieving accurate dimensional accuracy of scaffolds and maturing human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs), a primary source of functional cardiac cells. Drawing inspiration from cardi...

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Main Authors: Yong Wu, Yaning Wang, Miao Xiao, Guangming Zhang, Feixiang Zhang, Mingliang Tang, Wei Lei, Ziyun Jiang, Xiaoyun Li, Huiqi Zhang, Xiaoyi Ren, Yue Xu, Xiaotong Zhao, Chenxu Guo, Hongbo Lan, Zhenya Shen, Jianyi Zhang, Shijun Hu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
3D printing
engineered heart tissue
myocardial infarction
myocardium‐specific structure
Online Access:https://doi.org/10.1002/advs.202409871
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https://doi.org/10.1002/advs.202409871

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