Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re‐PHIRE

Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re‐PHIRE

Abstract Aims Despite receiving guideline‐directed medical heart failure (HF) therapy, patients with pulmonary hypertension associated with left heart disease (PH‐LHD) experience higher mortality and hospitalization rates than the general HF population. AZD3427 is a functionally selective, long‐acti...

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Main Authors: Marcin Ufnal, Kathleen Connolly, Marcus Millegard, Elena Surkova, Marco Guazzi, Diana Bonderman, Justin Ezekowitz, Finn Gustafsson, Michał Ciurzyński, Raquel López Vilella, Tariq Ahmad, Roy Gardner, Pavel Jansa, Sandra vanWijk, Koichiro Kinugawa, Erik Björklund, Zhi‐Cheng Jing, Stephan Rosenkranz
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:ESC Heart Failure
Subjects:
Heart failure
Left heart disease
Pulmonary hypertension
Pulmonary vascular resistance
Relaxin
Online Access:https://doi.org/10.1002/ehf2.15203
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https://doi.org/10.1002/ehf2.15203

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