Intra-Arterial Super-Selective Delivery of Yttrium-90 for the Treatment of Recurrent Glioblastoma: In Silico Proof of Concept with Feasibility and Safety Analysis

Intra-Arterial Super-Selective Delivery of Yttrium-90 for the Treatment of Recurrent Glioblastoma: In Silico Proof of Concept with Feasibility and Safety Analysis

<b>Background</b>: Intra-arterial cerebral infusion (IACI) of radiotherapeutics is a promising treatment for glioblastoma (GBM) recurrence. We investigated the in silico feasibility and safety of Yttrium-90-Poly(vinyl alcohol)-Microbubble (<sup>90</sup>Y-PVA-MB) IACI in patie...

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Main Authors: Giulia Paolani, Silvia Minosse, Silvia Strolin, Miriam Santoro, Noemi Pucci, Francesca Di Giuliano, Francesco Garaci, Letizia Oddo, Yosra Toumia, Eugenia Guida, Francesco Riccitelli, Giulia Perilli, Alessandra Vitaliti, Angelico Bedini, Susanna Dolci, Gaio Paradossi, Fabio Domenici, Valerio Da Ros, Lidia Strigari
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
glioblastoma
<sup>90</sup>Y microbubbles
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Online Access:https://www.mdpi.com/1999-4923/17/3/345
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