Combination of Adult Mesenchymal Stem Cell Therapy and Immunomodulation with Dimethyl Fumarate Following Spinal Cord Ventral Root Repair

Combination of Adult Mesenchymal Stem Cell Therapy and Immunomodulation with Dimethyl Fumarate Following Spinal Cord Ventral Root Repair

Spinal cord injury results in significant motor and sensory loss. In the experimental ventral root avulsion (VRA) model, the ventral (motor) roots are disconnected from the spinal cord surface, disrupting contact between spinal motoneurons and muscle fibers. Axotomized motoneurons typically degenera...

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Bibliographic Details
Main Authors: Paula Regina Gelinski Kempe, Mateus Vidigal de Castro, Lilian de Oliveira Coser, Luciana Politti Cartarozzi, Benedito Barraviera, Rui Seabra Ferreira, Alexandre Leite Rodrigues de Oliveira
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biology
Subjects:
spinal cord injury
stem cell therapy
gliosis
inflammation
Online Access:https://www.mdpi.com/2079-7737/13/11/953
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