Chronic lymphocytic leukemia (CLL) screening and abnormality detection based on multi-layer fluorescence imaging signal enhancement and compensation

Abstract Purpose Fluorescence in situ hybridization (FISH) plays a critical role in cancer screening but faces challenges in signal clarity and manual intervention. This study aims to enhance FISH signal clarity, improve screening efficiency, and reduce false negatives through an automated image acq...

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Bibliographic Details
Main Authors: Lemin Shi, Ping Gong, Mingye Li, Dianxin Song, Hao Zhang, Zhe Wang, Xin Feng
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Online Access:https://doi.org/10.1007/s00432-025-06150-9
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