De novo serine biosynthesis is protective in mitochondrial disease

De novo serine biosynthesis is protective in mitochondrial disease

Summary: The importance of serine as a metabolic regulator is well known for tumors and is also gaining attention in degenerative diseases. Recent data indicate that de novo serine biosynthesis is an integral component of the metabolic response to mitochondrial disease, but the roles of the response...

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Main Authors: Christopher B. Jackson, Anastasiia Marmyleva, Geoffray Monteuuis, Ryan Awadhpersad, Takayuki Mito, Nicola Zamboni, Takashi Tatsuta, Amy E. Vincent, Liya Wang, Nahid A. Khan, Thomas Langer, Christopher J. Carroll, Anu Suomalainen
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725004814
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http://www.sciencedirect.com/science/article/pii/S2211124725004814

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