Standardization of SARS-CoV-2 Nucleic Acid Amplification Techniques by Calibration and Quantification to the First WHO International Standard for SARS-CoV-2 RNA

Clinical decision-making regarding isolation of SARS-CoV-2 patients is usually based on semiquantitative cycle-threshold (Ct) values without standardization. However, not all molecular assays produce Ct values, and there is ongoing discussion about whether Ct values can be safely used for decision-m...

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Main Authors: Jolanda J. C. Voermans, Daphne G. J. C. Mulders, Rob J. J. Beerkens, Marlize van Duijn, Liesbeth van der Zwaan, Janette Rahamat-Langendoen, Annemiek van der Eijk, Marion P. G. Koopmans, Richard Molenkamp
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2023/7803864
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