Acute obstetric coagulopathy is associated with excess plasmin generation and proteolysis of fibrinogen and factor V

Acute obstetric coagulopathy is associated with excess plasmin generation and proteolysis of fibrinogen and factor V

Abstract: Hemostatic impairment may exacerbate postpartum hemorrhage (PPH). Previously, we described a distinct coagulopathy, associated with multiple causes of PPH including placental abruption and amniotic fluid embolus, termed acute obstetric coagulopathy (AOC). AOC is characterized by very high...

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Main Authors: Peter W. Collins, Claire S. Whyte, Lucy de Lloyd, Anuj Narwal, Sarah F. Bell, Nicholas Gill, Rachel E. Collis, Peter V. Jenkins, Nicola J. Mutch
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925000837
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