Design, synthesis, biological evaluation and in silico studies of 2-anilino- 4-(benzimidazol- 1-yl)pyrimidine scaffold as antitumor agents
Abstract In an attempt to rationalize the search for new potential Chemotherapeutic agents, a new series of 2-anilinobenzimidazol derivatives with CDK activity have been synthesized. The newly synthesized compounds have been assessed for their cytotoxic effects and CDK activity. These presented comp...
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| Main Authors: | Lamees S. Al-Rasheed, Siddique Akber Ansari, Hanadi H. Asiri, Ahmed H. Bakheit, Abdulrahman A. Al-mehizia, Amsha S. Alsegiani, Hamad M. Alkahtani |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
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| Series: | Saudi Pharmaceutical Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44446-025-00010-w |
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