Application of reverse cumulative distribution curve and scaled logit model in determining optimal immunogenic dose and prediction of protection of EV71 vaccines

Background This study proposes the reverse cumulative distribution curve (RCDC) for optimal dose selection and a scaled logit model for estimating protection in EV71 vaccine development.Research design and methods Data were from a phase 2 trial involving infants and young children randomized to rece...

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Bibliographic Details
Main Authors: Lairun Jin, Pengfei Jin, Xuefeng Zhang, Fengcai Zhu, Jingxin Li
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Expert Review of Vaccines
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/14760584.2024.2438760
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