Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs
IntroductionThe increasing resistance of Plasmodium falciparum to existing antimalarial drugs drives the urgent need for novel therapeutic strategies. The purine salvage pathway in P. falciparum is essential for the parasite’s survival due to its complete reliance on host-derived purines for nucleic...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Parasitology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpara.2025.1634209/full |
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