PELI2 inhibits colorectal cancer development through MAPK signaling pathway

Abstract Colorectal cancer is one of the most common malignant tumors worldwide. Colorectal cancer has a poor survival rate because it tends to metastasise to the liver and other organs. PELI2, an E3 ubiquitin ligase, is down-expressed in a variety of tumors. However, the role of PELI2 in colorectal...

Full description

Saved in:
Bibliographic Details
Main Authors: Jialin Liu, Shengyun Hu, Liangbo Zhao, Yanmei Yang, Guanghua Wu, Yimeng Duan, Xinrui Ma, Peiwen Wang, Zhiyong Zhang, Hong Zong
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-025-01294-3
Tags: Add Tag
No Tags, Be the first to tag this record!