Single-cell perspective on the Monocyte-to-HDL cholesterol ratio as a metastasis biomarker in papillary thyroid cancer

Single-cell perspective on the Monocyte-to-HDL cholesterol ratio as a metastasis biomarker in papillary thyroid cancer

Abstract Background Papillary thyroid carcinoma (PTC) is a globally widespread inflammation-related cancer, where lymph node metastasis (LNM) poses significant challenges to the prognosis of PTC. The role of the monocyte-to-high-density lipoprotein cholesterol ratio (MHR), a novel inflammation marke...

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Bibliographic Details
Main Authors: Zhi-kun Ning, Hao Yi, Tingting Yang, Jiang Liu, Shanshan Su, Ting He, Haoyu Huang, Minghao Xie, Hui Li, Ying Tang, Xiaoping Zhu, Xiang Min
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Thyroid papillary carcinoma
Single-cell RNA sequencing
High density lipoprotein
Monocyte
Lymph node metastasis
Online Access:https://doi.org/10.1186/s12885-025-14373-9
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https://doi.org/10.1186/s12885-025-14373-9

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