Just a SNP away: The future of in vivo massively parallel reporter assay

The human genome is largely noncoding, yet the field is still grasping to understand how noncoding variants impact transcription and contribute to disease etiology. The massively parallel reporter assay (MPRA) has been employed to characterize the function of noncoding variants at unprecedented scal...

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Bibliographic Details
Main Authors: Katherine N. Degner, Jessica L. Bell, Sean D. Jones, Hyejung Won
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Insight
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772892724000695
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