Multi-ligand simultaneous docking of Carica papaya leaf phytochemicals, Carpaine and Rutin reveal multi-mechanism inhibition of cancer proteins, BCL-2 and WWP1
Cancer remains a major global health concern due to chemotherapy resistance and toxicity from high-dose treatments. To overcome these challenges, new therapeutic strategies targeting key proteins in cancer progression are essential. This study evaluates two phytochemicals, Carpaine (Car) and Rutin (...
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| Main Authors: | Merla Sudha, Asmita Saha, Belaguppa Manjunath Ashwin Desai, Anil Ranu Mhashal, Pronama Biswas |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Phytomedicine Plus |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031325001010 |
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