Multi-ligand simultaneous docking of Carica papaya leaf phytochemicals, Carpaine and Rutin reveal multi-mechanism inhibition of cancer proteins, BCL-2 and WWP1

Cancer remains a major global health concern due to chemotherapy resistance and toxicity from high-dose treatments. To overcome these challenges, new therapeutic strategies targeting key proteins in cancer progression are essential. This study evaluates two phytochemicals, Carpaine (Car) and Rutin (...

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Bibliographic Details
Main Authors: Merla Sudha, Asmita Saha, Belaguppa Manjunath Ashwin Desai, Anil Ranu Mhashal, Pronama Biswas
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Phytomedicine Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667031325001010
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