Exploring therapeutic applications of PTEN, TMPRSS2:ERG fusion, and tumour molecular subtypes in prostate cancer management

Exploring therapeutic applications of PTEN, TMPRSS2:ERG fusion, and tumour molecular subtypes in prostate cancer management

BackgroundProstate cancer is defined by the suppression of genes that suppress tumours and the activation of proto-oncogenes. These are the hallmarks of prostate cancer, and they have been linked to numerous genomic variations, which lead to unfavourable treatment outcomes. Prostate cancer can be ca...

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Bibliographic Details
Main Authors: Fidelis Charles Bugoye, Rispah Torrorey-Sawe, Richard Biegon, Nazima Dharsee, Fidelice Mafumiko, Herry Kibona, Said Aboud, Kirtika Patel, Simeon Mining
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
Subjects:
tumour molecular subtype
PTEN
TMPRSS2:ERG
genome
immune response
prostate cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1521204/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1521204/full

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